- Soma - Aldous Huxley, Brave New World
- Moksha - Aldous Huxley, Island
- Moloko Plus - Anthony Burgess, A Clockwork Orange
- Can-D, Chew-Z - Philip K. Dick, The Three Stigmata of Palmer Eldritch
- D, Mex Hit - Philip K. Dick, A Scanner Darkly
- Vurt - Jeff Noon, Vurt
- Ecstacide, Faith Salts, Christendine, Buddhine, Algebrine, Authentium, Amnesol, Duetine, and many more - Stanislav Lem, The Futurological Congress
- Snow Crash - Neal Stephenson, Snow Crash*
- Kryptonite - Joe Shuster/Jerry Siegel, Superman
- Magic Potion - Albert Underzo/Rene' Goscinny, Asterix the Gaul
- Spice or Melange - Frank Herbert, Dune
- Glitterstim, Carsunum, Ryll Spices - Star Wars literary universe
- Number Twelve - Nick McDonell, Twelve
- Space Honey - Futurama
- Synthehol - Star Trek: The Next Generation
- Chemical -Ray Loriga, Tokyo Doesn't Love Us Anymore
- Abulinix - Benjamin Kunkel, Indecision
I like how almost all of this list is science fiction. I can think of one they missed: Dylar - Don DeLillo, White Noise. While hyperlinking this post, I came across this list of fictional medicines and drugs. It's a much longer list which draws from a broader range of sources, including songs, cartoons and video games
*currently reading
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